EnvisionTec 3D-Bioplotter®

The EnvisionTEC 3D-Bioplotter® system has been used since 2000 for a variety of medical applications. This family of bioprinters processes open-source biomaterials using air or mechanical pressure to a syringe, which can fabricate scaffolds to create tissue, organs and more. EnvisionTec bioprinters are extremely accurate with X-Y repeatability down to 1 μm. All models have been designed for use in a sterile biosafety cabinet, meet standards for clinical trials and offer build sizes up to 192.4 cubic inches.

In the clinical setting, patient CT or MRI scans are used to create STL files to print solid 3D models which can then be used as templates for implants. Tissue Engineering and Controlled Drug Release require 3D scaffolds with welldefined external and internal structures. The 3D-Bioplotter® has the capacity of fabricating scaffolds using the widest range of materials of any singular Rapid Prototyping machine, from soft hydrogels over polymer melts up to hard ceramics and metals. Complex inner patterns can easily be designed using the 3D-Bioplotter® software to both control the mechanical properties, increase cell adhesion, as well as improve the flow of nutrient media throughout the interconnecting pores of the printed implants.

 

EnvisionTec’s Starter & Developer Series: Bioprinters for the Research and EDU Environment

3D Bioprinting at Minuteman High School Lexington

From schools to corporations, EnvisionTEC customers are using 3D printing to help reshape the future and save lives.

Minuteman Regional Vocational Technical High School in Massachusetts has a Biotechnology program where students are able to use an EnvisionTEC 3D-Bioplotter Starter series for their bioprinting research efforts, which allows them to be at the cutting edge of science. Watch the video to learn more!

3D Bioprinting at Rutgers University

Rutgers is using a 3D bioprinter for groundbreaking medical research, including developing biomedical products for tissue and organ regeneration, the delivery of pharmaceutical agents and a commercial product for knee meniscus repair. Watch the video to learn more!

  • Materials Available
  • System Properties

3D-Bioplotter LT Support RG

A cellulose derivative for 3D printing sacrificial supports at low temperatures

3D-Bioplotter HT Support RG

A cellulose derivative for 3D printing sacrificial supports at high temperatures

3D-Bioplotter PCL 45K RG

A versatile thermoplastic materials for tissue engineering applications

3D-Bioplotter Silicone TG

A versatile technical-grade silicone that 3D prints objects with medium hardness

3D-Bioplotter HT PCL 80k MG

A versatile thermoplastic materials for tissue engineering applications

The 3D-Bioplotter family is made with high-quality components and is extremely reliable, allowing R&D to spend more time printing. Rahul Roy, a North American service and applications engineer and 3D-Bioplotter expert, credits the German engineering and manufacturing. The 3D-Bioplotter, he said, “is built like a battleship.”

  • A new user management allows users to both share projects, materials and patterns, as well as have their own separate set of files for improved overview and security.
  • Input of outer shapes through STL files.
  • Multi-part and multi-material capable through the use of an automatic tool changer and multiple print heads.
  • Database of volume support structures for complex shapes.
  • Database of inner patterns (user-editable) in the controlling software, avoiding requiring patterns in the STL files.
  • Complex inner pattern with straight lines, zig-zag shapes and wave forms as well as hexagon shapes, including shift functions for “in between the lines” printing
  • Database of materials (user-editable) with all process parameters.
  • Material life time control to avoid scaffold fabrication with degraded materials.
  • Individual temperature control of each printing head, both in the parking positions, as well as during printing
  • Temperature curves with up to 5 set points and waiting times.
  • Complete control of all printing parameters (temperature, pressure, speed, etc) through the software.
  • Automatic platform height control for petri dishes, well plates, as well as other printing surfaces.
  • Improved surface finish of fabricated parts using randomized start position in outer contours.
  • 2D Dot-Printing (Biopatterning) capability
  • Low-Temperature Print Head: 0° – 70°C (32° – 158°F) with disposable PE cartridges.
  • High-Temperature Print Head: 30° – 250°C (86° – 482°F) with reusable stainless steel cartridges.
  • UV Curing Head (365 nm).
  • Needle cleaning station, with automatic cleaning before and during the print project available.
  • Luer Lock needle tips, 0.1mm to 1.0mm inner diameter available.
  • Automatic recalibration of park position coordinates in extensively used 3D-Bioplotters (Manufacturer & Developer Series only).
  • LOG file creation after project completion with all relevant data.
  • Footprint (L x W x H): 976 x 623 x 773 mm (38.4 x 24.5 x 30.4 in.)
  • Weight: About 110 kg (243 lbs)